A police station in the middle of the red light district and the presence of numerous police on foot make the area reasonably safe, though if you wander into one of the many secluded pedestrian alleys you place yourself at risk. Be aware of your surroundings and do not travel alone into unfamiliar neighborhoods. Acting touristy in Tijuana's red light district is very likely to draw attention from predators.
That said, safety is not a huge concern here as long as you mind your surroundings. Keep walking west toward Av. Revolucion, and you'll find yourself in the Zona Norte. Stay alert to anyone following you on this route as muggings sometimes occur on First Street.
From the Tijuana Arch at the corner of Av. This part of the street is safe to walk at night because it is very well lit, except for the street signs, which can be difficult to see at night. But you can recognize the corner at Calle Coahuilla and Revolucion easily by checking for a few landmarks, including an Oxxo convenience store, Hotel de Santiago, and La Tropa Bar. Turn left west at that corner and you will be on Calle Coahuilla.
Then you're just one block away from all the action. Once you reach the next block at Av. Constitucion, you have two choices, head straight forward, towards Hong Kong, or take a quick, fun tour around the core of the Red Light District. From Calle Coahuila, if you turn left south at Constitucion, you will see a block full of "Paraditas" standing girls , lining the sidewalks trying to make eye contact with you.
Turn immediately right at the next corner onto the large alleyway, Callejon Coahuilla, where the vast majority of the street prostitutes are standing and waiting.
